The active center of enzymes
The active center is the region of the enzyme that binds to the substrate , and where catalysis occurs. It has the following characteristics:
- It is a very small part of the total volume of the enzyme.
- They are made up of amino acids that are close by the folds of the polypeptide chain, even if they were far away in the original chain.
- It has a three-dimensional structure in the shape of a hole in which the substrate fits.
- Some amino acids have radicals with chemical affinity for the substrate, which is why they attract it and establish weak bonds with it. When these links are broken, the products are separated from the active center.