The production of hormones is regulated by a feedback system or negative feedback, in such a way that when there is an excessive amount of a hormone, its production is inhibited.
The hypothalamus is the nerve center that directs this response and controls all the secretions of the endocrine system. The hypothalamus secretes neurohormones that stimulate the pituitary to secrete tropic hormones, which are released into the blood until they are received by a target organ (thyroid, gonads, etc.) that produces a response, such as secreting other hormones (thyroxine, hormones sexual, etc.). These hormones, in addition to performing their function in the body, are captured by the hypothalamus, which will be responsible for inhibiting their production.